peplexicon

The peptide reference for curious minds

Make sense of peptides.

What they are. What researchers are finding. What we still don’t know. Explore the science in language you can understand.

Your reading level. The same underlying evidence.

Sources within reach

Inspect the research behind published findings.

Uncertainty stays visible

A laboratory finding is not a proven human benefit.

A reference in progress

Coverage varies. Missing evidence is marked, not filled in.

Peptides 101

Start with the building blocks.

New to peptides? Explore an illustrated introduction to amino acids, peptide chains, and receptors.

Choose a stage beneath the model: building block, chain, or receptor. Change reading depth above for a different explanation.

Loading the interactive model. The lesson below is ready to read.
  1. 01

    One building block

    An amino acid is a small molecule. Think of it as a bead: connect several beads and you begin to make a chain.

  2. 02

    A chain with an order

    A peptide is a chain of amino acids joined by peptide bonds. The order of its building blocks matters—not all peptides are the same.

  3. 03

    A message a cell can receive

    Some peptides carry messages. A receptor is a protein that recognizes a signal and helps a cell respond. Not every peptide fits every receptor.

A mechanism is a starting point—not a treatment recommendation.

When you open a profile, ask what was studied, whether the findings came from humans or a laboratory, and what remains uncertain.

Lesson sources & model limitations

This is a teaching model, not an atom-by-atom representation of a particular peptide. Shape, color, and motion are illustrative.

Molecular Biology of the Cell: chemical components ↗The Cell: signaling molecules and receptors ↗

Research leaderboard

Most cited in the lexicon

Explore all peptides ↗

Ranked by source links attached to published findings—not visitor popularity, treatment quality, or proven benefit.

  1. 01SemaglutideGLP-1 receptor agonist1164evidence links
  2. 02Desmopressinvasopressin analog532evidence links
  3. 03LeuprolideGnRH agonist451evidence links
  4. 04TeriparatidePTH analog420evidence links
  5. 05Octreotidesomatostatin analog414evidence links
  6. 06LiraglutideGLP-1 receptor agonist413evidence links

Peptide library · live registry

Explore the peptide map.

Browse every peptide currently recorded in Peplexicon. Group related systems, filter regulatory state, and sort by the evidence we have actually published.

Live database registry191 peptide entitiesPopularity signal: not connected
191 peptides
Filtered Peplexicon peptide library
PeptideClassRegulatory statusEvidenceClaimsEvidence links
5-Amino-1MQNot yet published
NNMT inhibitorNot recordedNot yet publishedNot publishedNot published
AbaloparatideOpen profile ↗PTHrP analogNot recordedPublished evidence154157
ACE-031Open profile ↗myostatin inhibitor (ActRIIB)Not recordedPublished evidence2527
Acetyl Tetrapeptide-3Open profile ↗hair peptideNot recordedPublished evidence22
AdiponectinOpen profile ↗metabolic hormoneNot recordedPublished evidence117117
Alanyl-GlutamineOpen profile ↗dipeptideNot recordedPublished evidence4949
AlbiglutideOpen profile ↗GLP-1 receptor agonistNot recordedPublished evidence7273
AldesleukinOpen profile ↗IL-2 proteinNot recordedPublished evidence5759
AlexamorelinOpen profile ↗GHRPNot recordedPublished evidence1820
AmycretinOpen profile ↗GLP-1 + amylin single moleculeNot recordedPublished evidence2121
AnamorelinOpen profile ↗ghrelin agonistNot recordedPublished evidence106111
Angiotensin 1-7Open profile ↗RAS peptideNot recordedPublished evidence102103
AnserineOpen profile ↗dipeptide antioxidantNot recordedPublished evidence6060
AOD-9604Open profile ↗GH C-terminal fragmentNot approved; Phase 3 trial data negativePublished evidence1212
ApitegromabOpen profile ↗selective myostatin inhibitorNot recordedPublished evidence3236
ApraglutideOpen profile ↗GLP-2 analogNot recordedPublished evidence6870
ARA-290Open profile ↗EPO-derived peptideNot recordedPublished evidence67
ArgirelineOpen profile ↗SNAP-25 inhibitor peptideCosmetic ingredient — no drug approval requiredPublished evidence1313
BimagrumabOpen profile ↗ActRII antibodyNot recordedPublished evidence5052
Biotinoyl Tripeptide-1Open profile ↗hair peptideNot recordedPublished evidence44
BivalirudinOpen profile ↗thrombin inhibitor peptideNot recordedPublished evidence149153
BortezomibOpen profile ↗proteasome inhibitorNot recordedPublished evidence139143
BPC-157Open profile ↗gastric peptide fragmentCategory 2 (2023) — PCAC vote Jul 2026Published evidence116121
BradykininOpen profile ↗vasoactive peptideNot recordedPublished evidence133137
BronchogenOpen profile ↗bronchial peptide bioregulatorNot recordedPublished evidence55
CagrilintideOpen profile ↗amylin analogNot recordedPublished evidence98100
CagriSemaOpen profile ↗GLP-1 + amylin comboNot recordedPublished evidence6060
CalcitoninOpen profile ↗calcium-regulating hormoneNot recordedPublished evidence125127
CardiogenOpen profile ↗cardiac peptide bioregulatorNot recordedPublished evidence11
CarfilzomibOpen profile ↗proteasome inhibitor peptideNot recordedPublished evidence111113
CarnosineOpen profile ↗dipeptideGRAS as supplementPublished evidence8993
CarperitideOpen profile ↗ANP analogNot recordedPublished evidence6366
CerebrolysinOpen profile ↗neuropeptide mixtureNot recordedPublished evidence5353
CetrorelixOpen profile ↗GnRH antagonistNot recordedPublished evidence112117
ChonlutenOpen profile ↗bronchial peptide bioregulatorNot recordedPublished evidence33
CJC-1295Open profile ↗GHRH analogNot approvedPublished evidence1213
CJC-1295 DACNot yet published
GHRH analog (long-acting)Not approvedNot yet publishedNot publishedNot published
ColistinOpen profile ↗polymyxin antibioticNot recordedPublished evidence95101
ColivelinOpen profile ↗neuroprotective peptideNot recordedPublished evidence4445
Copper Tripeptide-1Open profile ↗copper-binding tripeptideCosmetic ingredientPublished evidence1717
CortagenOpen profile ↗peptide bioregulatorNot recordedPublished evidence66
CortexinOpen profile ↗cortical neuropeptide mixNot recordedPublished evidence4747
Creatine (tracked)Open profile ↗not peptide - trackedNot recordedPublished evidence66
DanuglipronOpen profile ↗oral GLP-1 small moleculeNot recordedPublished evidence7075
DaptomycinOpen profile ↗lipopeptide antibioticNot recordedPublished evidence130135
DecorinylNot yet published
decorin-mimic peptideNot recordedNot yet publishedNot publishedNot published
Defensin Alpha-1Open profile ↗antimicrobial peptideNot recordedPublished evidence1010
DegarelixOpen profile ↗GnRH antagonistNot recordedPublished evidence150155
DesmopressinOpen profile ↗vasopressin analogNot recordedPublished evidence471532
DihexaOpen profile ↗angiotensin IV-derived peptideNot evaluatedPublished evidence11
DSIPOpen profile ↗neuropeptideNot evaluatedPublished evidence2828
DulaglutideOpen profile ↗GLP-1 receptor agonistNot recordedPublished evidence148150
EfinopegdutideOpen profile ↗GLP-1/glucagon dual agonistNot recordedPublished evidence1212
ElafinOpen profile ↗protease inhibitor peptideNot recordedPublished evidence8284
ElcatoninOpen profile ↗calcitonin analogNot recordedPublished evidence3232
EpithalonOpen profile ↗tetrapeptideNot evaluatedPublished evidence77
EptifibatideOpen profile ↗antiplatelet peptideNot recordedPublished evidence101104
ExenatideOpen profile ↗GLP-1 receptor agonistNot recordedPublished evidence217230
EyeserylNot yet published
anti-puffiness peptideNot recordedNot yet publishedNot publishedNot published
Follistatin 315Open profile ↗activin antagonistNot recordedPublished evidence812
Follistatin 344Open profile ↗glycoprotein / activin antagonistNot evaluatedPublished evidence22
FOXO4-DRIOpen profile ↗D-retro-inverso peptide / senolyticNot evaluatedPublished evidence2323
GalaninOpen profile ↗regulatory neuropeptideNot recordedPublished evidence120123
GanirelixOpen profile ↗GnRH antagonistNot recordedPublished evidence104114
GDF-11Open profile ↗TGF-beta superfamily proteinNot evaluatedPublished evidence3032
GHK-CuOpen profile ↗copper-binding tripeptideAllowed in topicals; Category 2 for injectable (2024)Published evidence6363
GhrelinOpen profile ↗hunger hormoneNot recordedPublished evidence8787
GHRP-1Open profile ↗GHRPNot recordedPublished evidence3637
GHRP-2Open profile ↗GHRPNot approvedPublished evidence3132
GHRP-6Open profile ↗GHRPNot approvedPublished evidence3235
GlucagonOpen profile ↗glucagonNot recordedPublished evidence184196
GlutathioneOpen profile ↗antioxidant tripeptideNot recordedPublished evidence5252
Glycyl-GlutamineOpen profile ↗dipeptideNot recordedPublished evidence3434
GonadorelinOpen profile ↗GnRHNot recordedPublished evidence8181
GoserelinOpen profile ↗GnRH agonistNot recordedPublished evidence8991
Hexapeptide-11Open profile ↗cosmetic peptideNot recordedPublished evidence810
HexarelinOpen profile ↗GHRPNot approvedPublished evidence3030
HGH Fragment 176-191Open profile ↗GH C-terminal fragmentNot approvedPublished evidence22
HumaninOpen profile ↗mitochondrial-derived peptideNot evaluatedPublished evidence105106
IGF-1 DESNot yet published
IGF variantNot recordedNot yet publishedNot publishedNot published
IGF-1 LR3Open profile ↗IGF analogNot approvedPublished evidence22
InsulinOpen profile ↗metabolic hormoneNot recordedPublished evidence9498
Insulin GlargineOpen profile ↗long-acting insulinNot recordedPublished evidence165167
Insulin LisproOpen profile ↗rapid insulinNot recordedPublished evidence147156
IpamorelinOpen profile ↗GHRP / ghrelin mimeticNot approvedPublished evidence6161
KisspeptinOpen profile ↗neuropeptide / GnRH regulatorNot approvedPublished evidence105105
KlothoOpen profile ↗anti-aging proteinNot recordedPublished evidence6671
KPVOpen profile ↗alpha-MSH fragmentCategory 2 (2024)Published evidence2727
LanreotideOpen profile ↗somatostatin analogNot recordedPublished evidence130132
LarazotideOpen profile ↗zonulin antagonistPhase 3 completed; not yet approvedPublished evidence3642
LeptinOpen profile ↗satiety hormoneNot recordedPublished evidence7879
LeuphasylOpen profile ↗enkephalin analog peptideCosmetic ingredientPublished evidence1415
LeuprolideOpen profile ↗GnRH agonistNot recordedPublished evidence385451
LinaclotideOpen profile ↗GC-C agonistNot recordedPublished evidence172175
LiraglutideOpen profile ↗GLP-1 receptor agonistFDA Approved (Victoza 2010, Saxenda 2014)Published evidence361413
LivagenOpen profile ↗peptide bioregulatorNot recordedPublished evidence66
LixisenatideOpen profile ↗GLP-1 receptor agonistNot recordedPublished evidence104108
LL-37Open profile ↗cathelicidin antimicrobial peptideNot approvedPublished evidence99106
Lutetium Lu-177 DotatateOpen profile ↗radiolabeled SST peptideNot recordedPublished evidence4349
MacimorelinOpen profile ↗ghrelin agonistNot recordedPublished evidence99113
MagaininOpen profile ↗antimicrobial peptideNot recordedPublished evidence109115
Matrixyl 3000Open profile ↗matrikine signaling peptidesCosmetic ingredientPublished evidence1415
Matrixyl Synthe6Not yet published
matrikineNot recordedNot yet publishedNot publishedNot published
MazdutideOpen profile ↗GLP-1/glucagon dual agonistNot recordedPublished evidence6771
Melanotan IOpen profile ↗melanocortin agonistNot recordedPublished evidence1313
Melanotan IIOpen profile ↗melanocortin receptor agonist (non-selective)Not approvedPublished evidence2430
MelflufenOpen profile ↗peptide-drug conjugateNot recordedPublished evidence3746
MelittinOpen profile ↗antimicrobial/cytolytic peptideNot recordedPublished evidence124142
MGFOpen profile ↗IGF-1 splice variantNot evaluatedPublished evidence5757
MK-677Open profile ↗non-peptide ghrelin mimetic / GHSR agonistNot approved; Phase 3 data existsPublished evidence4044
MOTS-cOpen profile ↗mitochondrial-derived peptideNot evaluatedPublished evidence98102
N-Acetyl Selank AmidateNot yet published
tuftsin analogNot recordedNot yet publishedNot publishedNot published
N-Acetyl Semax AmidateNot yet published
ACTH analogNot recordedNot yet publishedNot publishedNot published
NafarelinOpen profile ↗GnRH agonistNot recordedPublished evidence4549
NesiritideOpen profile ↗BNP analogNot recordedPublished evidence5555
Neuropeptide YOpen profile ↗appetite neuropeptideNot recordedPublished evidence111114
NisinOpen profile ↗bacteriocin peptideNot recordedPublished evidence8787
NoopeptOpen profile ↗nootropic dipeptideNot recordedPublished evidence77
OctreotideOpen profile ↗somatostatin analogNot recordedPublished evidence340414
Oligopeptide-1Open profile ↗EGF peptideNot recordedPublished evidence78
Oligopeptide-2Open profile ↗IGF peptideNot recordedPublished evidence11
OmigananOpen profile ↗antimicrobial peptideNot recordedPublished evidence3738
Orexin AOpen profile ↗wakefulness neuropeptideNot recordedPublished evidence108110
OrforglipronOpen profile ↗oral non-peptide GLP-1Not recordedPublished evidence151168
OvagenOpen profile ↗liver/GI peptide bioregulatorNot recordedPublished evidence77
OxytocinOpen profile ↗neurohypophyseal hormoneNot recordedPublished evidence134135
P21Open profile ↗telomerase activator peptideNot evaluatedPublished evidence6970
PACAPOpen profile ↗pituitary adenylate cyclase peptideNot recordedPublished evidence125127
Palmitoyl Pentapeptide-4Open profile ↗matrikine signaling peptideCosmetic ingredientPublished evidence1212
PancragenOpen profile ↗pancreatic peptide bioregulatorNot recordedPublished evidence33
PasireotideOpen profile ↗somatostatin analogNot recordedPublished evidence126126
PE-22-28Not yet published
spadin analogNot recordedNot yet publishedNot publishedNot published
PEG-MGFOpen profile ↗PEGylated IGF-1 splice variantNot evaluatedPublished evidence11
PegvisomantOpen profile ↗GH receptor antagonistNot recordedPublished evidence9096
PemvidutideOpen profile ↗GLP-1/glucagon dual agonistNot recordedPublished evidence3333
Pentadecapeptide BPC 157 ArginateNot yet published
gastric peptide saltNot recordedNot yet publishedNot publishedNot published
Pentosan PolysulfateOpen profile ↗glycosaminoglycanNot recordedPublished evidence112113
PexigananOpen profile ↗antimicrobial peptideNot recordedPublished evidence3743
PinealonOpen profile ↗peptide bioregulatorNot recordedPublished evidence11
PlecanatideOpen profile ↗GC-C agonistNot recordedPublished evidence5959
PlitidepsinOpen profile ↗cyclic depsipeptideNot recordedPublished evidence7478
Polymyxin BOpen profile ↗antimicrobial peptideNot recordedPublished evidence160163
PramlintideOpen profile ↗amylin analogNot recordedPublished evidence5662
ProstamaxNot yet published
prostate peptide bioregulatorNot recordedNot yet publishedNot publishedNot published
PT-141Open profile ↗melanocortin receptor agonistFDA Approved (Vyleesi 2019) for HSDD in premenopausal womenPublished evidence1014
RelamorelinOpen profile ↗ghrelin agonistNot recordedPublished evidence2430
RetatrutideOpen profile ↗GLP-1/GIP/glucagon triple receptor agonistPhase 3 trials ongoing (2026)Published evidence8485
RG-92Open profile ↗immune peptideNot recordedPublished evidence11
RomidepsinOpen profile ↗cyclic peptide HDAC inhibitorNot recordedPublished evidence9596
SelankOpen profile ↗tuftsin analogNot evaluatedPublished evidence1010
SemaglutideOpen profile ↗GLP-1 receptor agonistFDA Approved (Ozempic 2017, Wegovy 2021, Rybelsus 2019)Published evidence10461164
SemaxOpen profile ↗ACTH analogNot evaluatedPublished evidence2121
SermorelinOpen profile ↗GHRH analogPreviously FDA approved (withdrawn 2008); compounded widelyPublished evidence78
SetmelanotideOpen profile ↗MC4R agonistNot recordedPublished evidence7980
SigumirOpen profile ↗cartilage peptide bioregulatorNot recordedPublished evidence22
SLU-PP-332Open profile ↗ERR agonistNot recordedPublished evidence2425
SNAP-8Not yet published
SNARE complex inhibitor peptideCosmetic ingredientNot yet publishedNot publishedNot published
SomatostatinOpen profile ↗inhibitory hormoneNot recordedPublished evidence147147
SS-31Open profile ↗mitochondria-targeting peptidePhase 3 (heart failure); Breakthrough Therapy designationPublished evidence8791
Substance POpen profile ↗tachykinin neuropeptideNot recordedPublished evidence9494
SurvodutideOpen profile ↗GLP-1/glucagon dual agonistNot recordedPublished evidence5558
Syn-AkeOpen profile ↗synthetic waglerin-1 analogCosmetic ingredientPublished evidence33
Syn-CollNot yet published
collagen-boosting peptideNot recordedNot yet publishedNot publishedNot published
Syn-TacksNot yet published
matrikine blendNot recordedNot yet publishedNot publishedNot published
TabimorelinOpen profile ↗ghrelin agonistNot recordedPublished evidence3338
TB-500Open profile ↗thymosin fragmentNot evaluatedPublished evidence88
TeduglutideOpen profile ↗GLP-2 analogNot recordedPublished evidence148157
TeicoplaninOpen profile ↗glycopeptide antibioticNot recordedPublished evidence119119
TeriparatideOpen profile ↗PTH analogNot recordedPublished evidence365420
TerlipressinOpen profile ↗vasopressin analogNot recordedPublished evidence117120
TesamorelinOpen profile ↗GHRH analogFDA Approved (Egrifta 2010) for HIV-associated lipodystrophyPublished evidence92104
TesofensineOpen profile ↗monoamine reuptake inhibitorNot recordedPublished evidence1617
TestagenNot yet published
reproductive peptide bioregulatorNot recordedNot yet publishedNot publishedNot published
ThymagenNot yet published
thymic bioregulatorNot recordedNot yet publishedNot publishedNot published
ThymalinOpen profile ↗thymic peptide bioregulatorNot recordedPublished evidence77
ThymopentinOpen profile ↗thymic pentapeptideNot recordedPublished evidence4750
Thymosin Alpha-1Open profile ↗thymic peptideApproved in 35+ countries; Category 2 USA (2024)Published evidence5454
Thymosin Beta-4Open profile ↗thymosinPhase 2 completed (wound healing); not approvedPublished evidence5050
TirzepatideOpen profile ↗GIP/GLP-1 dual receptor agonistFDA Approved (Mounjaro 2022, Zepbound 2023)Published evidence291310
TrestoloneOpen profile ↗anabolic (not peptide)Not recordedPublished evidence2727
TriptorelinOpen profile ↗GnRH agonistNot recordedPublished evidence155159
TuftsinOpen profile ↗phagocytosis peptideNot recordedPublished evidence7887
UbiquitinOpen profile ↗regulatory proteinNot recordedPublished evidence9494
UlaritideOpen profile ↗urodilatin analogNot recordedPublished evidence3138
VancomycinOpen profile ↗glycopeptide antibioticNot recordedPublished evidence217245
VasopressinOpen profile ↗neurohypophyseal hormoneNot recordedPublished evidence172195
VesugenOpen profile ↗peptide bioregulatorNot recordedPublished evidence11
VialoxOpen profile ↗muscle-relax peptideNot recordedPublished evidence1314
VilonOpen profile ↗peptide bioregulatorNot recordedPublished evidence88
VIPOpen profile ↗neuropeptideNot approvedPublished evidence7478
Zinc ThymulinOpen profile ↗thymic peptideNot recordedPublished evidence55
How to read these numbers

One evidence edge attached to a claim in the current immutable published profile; it is not a count of all literature on the peptide. Peplexicon does not yet collect a defensible popularity signal.

From the lexicon

Recently published updates

View the research brief ↗

New updates will appear here after publication.

Understanding, not a sales pitch

Read the science.
Keep the questions.

Peplexicon is an educational reference, not a treatment recommendation. Profiles distinguish published findings from unanswered questions. Automated processing does not mean clinical review.

How we handle evidence →Our publication standards →