peplexicon
Choose your depth

Context, anatomy, and key evidence

← Peptide library

regulatory neuropeptide

Galanin

Published evidence · coverage incomplete
Anatomical contextAnatomy connections are not mapped yet.

No body region is highlighted until this profile has a supported anatomical connection. This does not mean the peptide has no biological effects.

Read published mechanism findings ↓

At a glance

What is it—and why does it matter?

In a single-protein binding assay to human GalR1, CHEMBL501079 showed very high (sub-nanomolar) affinity, reported as Ki 0.03 nM.

Sources for this introduction: [1]

This published profile is a reference in progress. Findings retain their source context; missing topics are marked below.

What is it?

A molecule, not a product name.

This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.

How does it work?

Target, response, and disposition.

Mechanism

In a single-protein binding assay to human GalR1, CHEMBL501079 showed very high (sub-nanomolar) affinity, reported as Ki 0.03 nM.

Sources[1]chembl-activitiesChEMBL activities for CHEMBL501079Molecule: CHEMBL501079 Target: Galanin receptor type 2 (CHEMBL3176) Assay: Displacement of radiolabeled galanin from human galanin 2 receptor Assay format: single protein format Standard result: Ki = 3.2 nM pChEMBL value: 8.49 Document: CHEMBL1140203[1]chembl-activitiesChEMBL activities for CHEMBL501079Molecule: CHEMBL501079 Target: Galanin receptor type 2 (CHEMBL3176) Assay: Binding affinity to human GalR2 Assay format: single protein format Standard result: Ki = 0.9 nM pChEMBL value: 9.05 Document: CHEMBL1156930[1]chembl-activitiesChEMBL activities for CHEMBL501079Molecule: CHEMBL501079 Target: Galanin receptor type 1 (CHEMBL4894) Assay: Binding affinity to human GalR1 Assay format: single protein format Standard result: Ki = 0.03 nM pChEMBL value: 10.52 Document: CHEMBL1156930[1]chembl-activitiesChEMBL activities for CHEMBL501079Molecule: CHEMBL501079 Target: Galanin receptor type 1 (CHEMBL4894) Assay: Displacement of radiolabeled galanin from human galanin 1 receptor Assay format: single protein format Standard result: Ki = 0.35 nM pChEMBL value: 9.46 Document: CHEMBL1140203
Reported result
Ki = 3.2 nM
Source records
4
Independent studies
1

Evidence boundary: Applies only to the source-defined population, formulation, dose, and assessment period.

Exact passages, locators, and provenance
  1. supports · Source-backed record
    “Molecule: CHEMBL501079 Target: Galanin receptor type 2 (CHEMBL3176) Assay: Displacement of radiolabeled galanin from human galanin 2 receptor Assay format: single protein format Standard result: Ki = 3.2 nM pChEMBL value: 8.49 Document: CHEMBL1140203”

    ChEMBL activities for CHEMBL501079 · Activity 2381322

    chembl-activities:chembl501079:210a05b5bc45:210a05b5bc45
  2. supports · Source-backed record
    “Molecule: CHEMBL501079 Target: Galanin receptor type 2 (CHEMBL3176) Assay: Binding affinity to human GalR2 Assay format: single protein format Standard result: Ki = 0.9 nM pChEMBL value: 9.05 Document: CHEMBL1156930”

    ChEMBL activities for CHEMBL501079 · Activity 3124713

    chembl-activities:chembl501079:210a05b5bc45:210a05b5bc45
  3. supports · Source-backed record
    “Molecule: CHEMBL501079 Target: Galanin receptor type 1 (CHEMBL4894) Assay: Binding affinity to human GalR1 Assay format: single protein format Standard result: Ki = 0.03 nM pChEMBL value: 10.52 Document: CHEMBL1156930”

    ChEMBL activities for CHEMBL501079 · Activity 3123963

    chembl-activities:chembl501079:210a05b5bc45:210a05b5bc45
  4. supports · Source-backed record
    “Molecule: CHEMBL501079 Target: Galanin receptor type 1 (CHEMBL4894) Assay: Displacement of radiolabeled galanin from human galanin 1 receptor Assay format: single protein format Standard result: Ki = 0.35 nM pChEMBL value: 9.46 Document: CHEMBL1140203”

    ChEMBL activities for CHEMBL501079 · Activity 2381372

    chembl-activities:chembl501079:210a05b5bc45:210a05b5bc45

What has been studied?

What the evidence says.

This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.

Risks and interactions

Risks, organized for scanning.

This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.

Products and regulatory status

Same ingredient. Different records.

This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.

Administration context

The practical clinical context.

This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.

Research status + gaps

What still needs better answers?

  • No publishable claim yet for: administration, contraindication, effect, identity, interaction, regulatory, safety
  • 38 compiled claim(s) withheld by automated assurance: assurance_score_below_0.58 (29), assurance_score_below_0.72 (7), current_regulatory_source_required (6), extraction_ambiguity (34), high_risk_requires_regulatory_or_two_independent_sources (7), no_direct_support (35)

These are the limits of this profile, not an exhaustive list of scientific uncertainties.

References + discovery

Open the records yourself.

  1. ChEMBL activities for CHEMBL501079 ↗

    chembl-activities · published 2026-08-26 · retrieved 2026-08-26T20:13:52Z

Publication history and provenance

Version 3 · Automated assessment · 2026-09-04T19:33:33Z

2bf2728e77ff1828ba853163474ed8f63a3aed44d980df5d704de30c5533f283