At a glance
What is it—and why does it matter?
The reported kred quantifies the reaction rate for oxoMn(IV) reduction; glutathione’s kred was 130000.0 M-1 s-1 in this assay. pKa is the acid dissociation constant on a log scale; here, glutathione’s pKa was measured as 8.75.
Sources for this introduction: [1] [2]
This published profile is a reference in progress. Findings retain their source context; missing topics are marked below.
What is it?
A molecule, not a product name.
This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.
How does it work?
Target, response, and disposition.
Mechanism
The reported kred quantifies the reaction rate for oxoMn(IV) reduction; glutathione’s kred was 130000.0 M-1 s-1 in this assay.
- Reported result
- kred = 130000.0 M-1 s-1
- Source records
- 1
- Independent studies
- 1
Evidence boundary: Applies only to the source-defined population, formulation, dose, and assessment period.
Exact passages, locators, and provenance
- supports · Source-backed record
“Molecule: CHEMBL1543 Target: ADMET (CHEMBL612558) Assay: The compound was evaluated for the rate of oxoMn (IV) reduction Assay format: assay format Standard result: kred = 130000.0 M-1 s-1 Document: CHEMBL1129224”
ChEMBL activities for CHEMBL1543 · Activity 267700
chembl-activities:chembl1543:cc9464d448d3:cc9464d448d3
Pharmacokinetics
pKa is the acid dissociation constant on a log scale; here, glutathione’s pKa was measured as 8.75.
- Reported result
- pKa = 8.75
- Source records
- 1
- Independent studies
- 1
Evidence boundary: Applies only to the source-defined population, formulation, dose, and assessment period.
Exact passages, locators, and provenance
- supports · Source-backed record
“Molecule: CHEMBL1543 Target: No relevant target (CHEMBL2362975) Assay: pKa value was determined Assay format: small-molecule physicochemical format Standard result: pKa = 8.75 Document: CHEMBL1134179”
ChEMBL activities for CHEMBL1543 · Activity 470001
chembl-activities:chembl1543:cc9464d448d3:cc9464d448d3
What has been studied?
What the evidence says.
This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.
Risks and interactions
Risks, organized for scanning.
This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.
Products and regulatory status
Same ingredient. Different records.
This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.
Administration context
The practical clinical context.
This profile does not yet contain a published summary for this topic. This is a coverage gap, not evidence that no research exists.
Research status + gaps
What still needs better answers?
- No publishable claim yet for: administration, contraindication, effect, identity, interaction, regulatory, safety
- 29 compiled claim(s) withheld by automated assurance: assurance_score_below_0.58 (22), assurance_score_below_0.72 (6), current_regulatory_source_required (5), extraction_ambiguity (26), high_risk_requires_regulatory_or_two_independent_sources (6), no_direct_support (27)
These are the limits of this profile, not an exhaustive list of scientific uncertainties.
References + discovery
Open the records yourself.
- ChEMBL activities for CHEMBL1543 ↗
chembl-activities · published 2026-08-27 · retrieved 2026-08-27T19:16:08Z
Publication history and provenance
Version 3 · Automated assessment · 2026-08-27T19:16:08Z
69c96dda1483d50df3eec9f739a0b8bf9e4926e18dba660e5ba349766862dc73