Peplexicon Explains
Narrated explainers on how peptides work, the GLP-1 medicines and the peptides people ask about most. Each one lists its sources under the player.
10 videos · 16 minutes · Educational, not medical advice
1:50EP 10 · NewestSemaglutide vs tirzepatide: the only fair comparisonThe headline weight-loss numbers come from different trials. What a head-to-head trial shows, and why an average does not predict one person's result.What peptides are, how they work, and how they get into the body.
1:10EP 01What is a peptide?A peptide is a short chain of amino acids, and the order of those building blocks decides what it does.
1:01EP 02How a receptor worksPeptide medicines act from outside the cell: a key that fits one receptor, switches it on or blocks it, and is built to last.
1:40EP 07Why most peptide drugs are shotsA swallowed peptide is digested like food, so most peptide drugs are injected. The few pills work through clever chemistry, or by not being peptides at all.
1:39EP 08Insulin: one chain, cut in twoThe body makes insulin as one long chain and cuts out the middle. The story of the 1922 patient, the Nobel Prize, and why the FDA now calls insulin a protein.The names, the biology, the history and the trials behind today's GLP-1 medicines.
1:31EP 03“GLP-2” and “GLP-3”, decodedThere is no hormone called GLP-3. The nicknames count how many body signals a medicine copies.
1:09EP 04One gene, two tissues: the biology of GLP-1GLP-1 comes from the same gene as glucagon, lasts about two minutes in the blood, and was re-engineered to last a week.
1:18EP 05From lizard venom to a weekly shotHow a hormone found in the glucagon gene and a peptide from Gila monster venom became today's GLP-1 medicines.1:50EP 10Semaglutide vs tirzepatide: the only fair comparisonThe headline weight-loss numbers come from different trials. What a head-to-head trial shows, and why an average does not predict one person's result.How to judge a claim, and one much-hyped peptide put through it.
2:31EP 06BPC-157: what the evidence actually saysPromising in rats, unproven in people: the animal studies, the handful of human reports, where regulators stand, and why the vial is the biggest practical risk.
2:00EP 09From rats to people: how a peptide earns its evidenceEvidence climbs a ladder from the lab and animals to randomized trials. How few promising findings reach the top, and how to read a peptide claim.